Synthetic CBD Can Treat Seizures According To New Research

Synthetic CBD Can Treat Seizures According To New Research

A synthetic, non-intoxicating analogue of cannabidiol can effectively treat seizures, according to new research with rats.

The synthetic CBD alternative is easier to purify than a plant extract, eliminates the need to use agricultural land for hemp cultivation, and could avoid legal complications with cannabis-related products.

“It’s a much safer drug than CBD, with no abuse potential and doesn’t require the cultivation of hemp,” says Mark Mascal, professor in the chemistry department at the University of California, Davis.

“Unlike CBD, there is no way to convert H2CBD to intoxicating THC.”


 Get The Latest By Email

Weekly Magazine Daily Inspiration

Products containing CBD have recently become popular for their supposed health effects and because the compound does not cause a high. CBD is also being investigated as a pharmaceutical compound for conditions including anxiety, epilepsy, glaucoma, and arthritis.

But because it comes from extracts of cannabis or hemp plants, CBD poses legal problems in some states and under federal law. It is also possible to chemically convert CBD to tetrahydrocannabinol (THC), the intoxicating compound in marijuana.

8,9-Dihydrocannabidiol (H2CBD) is a synthetic molecule with a similar structure to CBD. Mascal’s laboratory developed a simple method to inexpensively synthesize H2CBD from commercially available chemicals.

“Unlike CBD, there is no way to convert H2CBD to intoxicating THC,” he says.

One important medical use of cannabis and CBD is in treatment of epilepsy. The US Food and Drug Administration has approved an extract of herbal CBD for treating some seizure conditions and there is also strong evidence from animal studies.

The researchers tested synthetic H2CBD against herbal CBD in rats with induced seizures. Researchers found H2CBD and CBD equally effective for the reduction of both the frequency and severity of seizures.

Mascal is working with colleagues to carry out more studies in animals with a goal of moving into clinical trials soon. UC Davis has applied for a provisional patent on anti-seizure use of H2CBD and its analogues, and Mascal has founded a company, Syncanica, to continue development.

The work appears in the journal Scientific Reports. Additional coauthors are from UC Davis and the University of Reading.

Source: UC Davis

books_herbs

 

AVAILABLE LANGUAGES

English Afrikaans Arabic Chinese (Simplified) Chinese (Traditional) Danish Dutch Filipino Finnish French German Greek Hebrew Hindi Hungarian Indonesian Italian Japanese Korean Malay Norwegian Persian Polish Portuguese Romanian Russian Spanish Swahili Swedish Thai Turkish Ukrainian Urdu Vietnamese

follow InnerSelf on

facebook icontwitter iconyoutube iconinstagram iconpintrest iconrss icon

 Get The Latest By Email

Weekly Magazine Daily Inspiration

Wednesday, 26 July 2023 17:18

Do you know why junk food is so addictive? Are you craving sweets yet? If you've ever wondered why junk food can be so addictive, you're not alone.

Thursday, 13 May 2021 08:34

Iron deficiency is a common nutritional disorder worldwide, and pre-menopausal women are most at risk of being diagnosed with it.

Thursday, 15 April 2021 07:10

Blooming flowers, chirping birds and long-awaited rays of sunshine: The first signs of spring are often greeted with joy. But soon comes the realization that with warm weather comes ticks. 

Friday, 02 April 2021 08:02

  Microdosing has become something of a wellness trend in recent years. The practice involves taking a low dose of a psychedelic drug to enhance performance, or reduce stress and anxiety.

Wednesday, 05 May 2021 08:15

While our immune system and antibiotics both do a great job of helping us fight life-threatening infections, the emergence of antibiotic resistance is quickly making it more difficult to cure...

Saturday, 08 May 2021 08:43

Humanity has always had a rocky relationship with wasps. They are one of those insects that we love to hate. We value bees (which also sting) because they pollinate our crops and make honey

New Attitudes - New Possibilities

InnerSelf.comClimateImpactNews.com | InnerPower.net
MightyNatural.com | WholisticPolitics.com | InnerSelf Market
Copyright ©1985 - 2021 InnerSelf Publications. All Rights Reserved.